A new install of minicom from Macports failed to make a config file with the -s option.
Here is a basic config file’s contents
# Machine-generated file - use "minicom -s" to change parameters.
pu port /dev/tty.usbserial-FTCCCT58
pu baudrate 38400
pu mretries 3
pu updir /home/david/tmp
pu downdir /home/david/tmp
pu tfcolor CYAN
pu tbcolor BLUE
NOTE : Just touching the file will work just as well. You may need to CHMOD it after